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Cryptolepine, isolated from sida acuta, sensitizes human gastric adenocarcinoma cells to TRAIL-induced apoptosis
(Wiley Online Library, 2010)
Bioassay guided separation of sida acuta whole plants led to the isolation of an alkaloid, cryptolepine (1), along with two kaempferol glycosides (2–3). Compound 1 showed strong activity in overcoming TRAIL-resistance in ...