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dc.contributor.authorKerns, Edward H.
dc.contributor.authorDi, Li
dc.date.accessioned2020-08-11T09:48:52Z
dc.date.available2020-08-11T09:48:52Z
dc.date.issued2008
dc.identifier.citationKerns, Edward H. and Di, Li (2008). Drug-like properties: concepts, structure design and methods from ADME to toxicity optimization. New York : Elsevier.en_US
dc.identifier.isbn978-0-1236-9520-8
dc.identifier.urihttp://hdl.handle.net/123456789/1363
dc.description.abstractDrug research is a fulfilling career because new drugs can improve human health, quality of life, and life span. For scientists dedicated to drug research, it can also be a supremely challenging mission, owing to the numerous attributes that must be simultaneously optimized to arrive at an efficacious drug-like compound. ADME/Tox (absorption, distribution, metabolism, elimination, toxicity) is one of these challenges. Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, typically only a fraction of these have sufficient ADME/Tox properties to become a drug product. This book is devoted to providing you, the drug research scientist or student, with an introduction to ADME/Tox property concepts, structure design, and methodology to help you succeed with these challenges.en_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.subjectPharmaceutical chemistryen_US
dc.subjectDrugs—structure-activity relationshipsen_US
dc.subjectDrug developmenten_US
dc.subjectDrugs—designen_US
dc.titleDrug-like properties: concepts, structure design and methods from ADME to toxicity optimizationen_US
dc.typeBooken_US


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