عرض سجل المادة البسيط

dc.contributor.authorAhmed, Firoj
dc.contributor.authorToume, Kazufumi
dc.contributor.authorOhtsuki, Takashi
dc.contributor.authorRahman, Mahmudur
dc.contributor.authorSadhu, Samir Kumar
dc.contributor.authorIshibashi, Masami
dc.date.accessioned2014-08-19T23:20:56Z
dc.date.available2014-08-19T23:20:56Z
dc.date.issued2010
dc.identifier.citationWiley Online Library, 2010en_US
dc.identifier.urihttp://hdl.handle.net/123456789/258
dc.description.abstractBioassay guided separation of sida acuta whole plants led to the isolation of an alkaloid, cryptolepine (1), along with two kaempferol glycosides (2–3). Compound 1 showed strong activity in overcoming TRAIL-resistance in human gastric adenocarcinoma (AGS) cells at 1.25, 2.5 and 5 μm. Combined treatment of 1 and TRAIL sensitized AGS cells to TRAIL-induced apoptosis at the aforementioned concentrations.en_US
dc.language.isoenen_US
dc.publisherWiley Online Libraryen_US
dc.subjectSida acutaen_US
dc.subjectMalvaceaeen_US
dc.subjectCryptolepineen_US
dc.subjectTRAIL-induced apoptosisen_US
dc.subjectAGS cell linesen_US
dc.titleCryptolepine, isolated from sida acuta, sensitizes human gastric adenocarcinoma cells to TRAIL-induced apoptosisen_US
dc.typeArticleen_US


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عرض سجل المادة البسيط