Phytopharmacological evaluation of leaves of olive-olea europaea

Abstract

The ethanol extract of Olea europaea of the family Oleaceae has been evaluated for the presence of bioactive secondary metabolites by using standard chromogenic reagent and cytotoxicity by brine shrimp lethality bioassay. The ethanol extract of the plant indicated the presence of alkaloids, steroids, flavonoids and tannins. The plant extract exhibited significant cytotoxic effect on brine shrimp lethality bioassay, where the plant extract showed LC50 of 263.4 and 13.09 µg/ml after 18 and 24 hours respectively. For the standard carboplatin, LC50 were found 70.21 and 0.45 µg/ml respectively after 18 hours and 24hours.